Signs and symptoms of hemophilia. Hemophilia is a disease that causes bleeding disorders due to lack of clotting factors. As a result, bleeding lasts longer when the body is injured.
Under normal circumstances, the protein that becomes the blood clotting factor forms a retaining net around the platelets (blood cells) that can freeze the blood and eventually stop the bleeding.
Blood clots result in prolonged and prolonged bleeding, this is due to a lack of protein in people with hemophilia
Hemophilia is a congenital disease commonly experienced by men. This disease can be lowered due to gene mutations that result in changes in the DNA strands (chromosomes) that make the process in the body is not running normally.
Mutation of this gene can come from the father, mother, or both parents. There are many types of hemophilia, but the most common types are hemophilia A and B. The severity of the hemophilia sufferers depend on the number of clotting factors in the blood.
The less the amount of blood clotting factor, the more severe hemophilia. The less the amount of blood clotting factor, the more severe hemophilia. the patient can live normally during the treatment of signs and symptoms of hemophilia and avoid any conditions that trigger hemorrhage.
Signs and symptoms of hemophilia
bouts that are difficult to stop or last longer are signs and symptoms of hemophilia, such as nose bleeding, muscle, gum, or joints. The severity of bleeding depends on the amount of freezing factor in the blood.
In mild hemophilia, the number of clotting factors ranges from 5-50%. Signs and symptoms of hemophilia in the form of prolonged bleeding appear when patients suffer injuries or post medical procedures, such as surgery.
In moderate hemophilia, the number of clotting factors ranges from 1-5%. Signs and Symptoms of Hemophilia that may appear include:
- Easy skin bruising.
- Bleeding in the area around the joint.
- Tingling and mild pain in the knees, elbows, and ankles.
The last type of hemophilia is severe hemophilia with a total clotting factor of less than 1%. Patients usually often experience spontaneous bleeding, such as bleeding gums, nosebleeds, or bleeding joints and muscles for no apparent reason. Symptoms of bleeding that need to be aware of are bleeding in the skull (intracranial hemorrhage). Symptoms are characterized by severe headaches, vomiting, stiff neck, paralysis in part or all of the facial muscles, and double vision.
The process of blood coagulation requires elements in the blood, such as platelets and blood plasma proteins.
In the case of hemophilia, there are gene mutations that cause the body to lack certain clotting factors in the blood. The cause of hemophilia A is a gene mutation occurring in clotting factor VI While hemophilia B is caused by mutations that occur in the clotting factor IX (9) in the blood.